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The mean baseline body weight was 235 pounds and the trial lasted 68 weeks

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doi:10.1038/nmicrobiol.2016.93 [15] Ramos CI, Armani RG, Canziani ME, et al

This result contrasts with some previous studies on DSIPs neuroprotective effects that have reported reduction in infarct size in other models [1]

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LTP is thus localized at sites where NMDA channels are opened by active synaptic inputs that are releasing glutamate and causing depolarization of the postsynaptic cell, and will not affect nearby inactive synapses